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Do you spot what and where to record on the timeline with fake blank regions, and then replace those blank regions while recording (if your recording foley) and with your edited sfx?
Or do you just spot with markers or on the paper?
I find that spotting (and create regions as marker-place) on the timeline take more time, but in the end the results are more precise and the time spent planning is well rewarded in the end.
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I do spot with blank regions, though I don't eschew markers. Here's the upside to groups:
edicue We use edicue for our ADR, foley and sfx cueing, and the workflow requires region groups. Edicue is great for spotting other things as well though, and has department note functionality built in. The program takes the region groups and outputs nice pretty pdf reports with timecodes, or can spit out a tab delimited text file. This solves the databasing and transcription issues that Tim has to deal with, though it is a third party solution.
Multiple tracks. I can spot different tracks for different departments, so foley, sound design, and dialogue can all get their own tracks with notes. This would be true even without edicue.
Color Coding. A common footstep foley workflow for me is to spot the feet per character and surface with region groups, then change the color of the groups away from the default color of the tracks (usually per surface). As we cut the foot foley, we drag the recorded file down to the character track and set it on top of the empty group, overwriting it. In this way we can tell at a glance what's been recorded and what's left to do.
in and out points. Markers only give you one point of reference at a time. region groups give you ins and outs.
I don't spot with blank regions, simply because i find it a hassle.
Furthermore i'm afraid i could confuse a low amplitude region with an empty one.
What i do create are midi region's to keep track of specific spots that either:
need more design attention. Or some other practical reason for looking at, for example:
a region could be named "temp visuals" to remind myself that not everything needs to be sync
in that timeframe.