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As its not really possible to work in exactly the same way in PT and Nuendo, it really isn't that helpful.
We actually started out trying to. But our layout has since evolved into its own system. Some parts are still loosely based on the PT keyset like zoom, top/tail, crossfade and the simple drop marker. It makes it easier for first timers.
Otoh I never found the cubendo default layout to be very helpful in post.
The more intuitive and logical you can make the reasoning behind how you set the keyboard up the easier it will be to remember.
Make sure all your favourite editing and mixing commands are easily accessible. Read through ALL the available key commands from time to time. You WILL find new clever ways to deal with complex situations easier and faster. Don't overlook the power of macros and the project logical editor. It can do magic stuff :).
I do believe in the keybindings section of nuendo there is a "protools" preset, but I have found that they do not really transfer well and you just end up lost trying to use pro tools key bindings in nuendo.