There is a particular episode of the Radiolab Podcast that interviews two blind men with opposing coping mechanisms for blindness: one, Zoltan, cannot fathom living in the world without picturing it and creates an image for everything and everyone he interacts with; the other, John, hates the idea of fantasizing an inaccurate image for his world and attempts to forget about the concept of sight altogether. For those who are interested, HERE is the link—it's a fascinating 20 minutes of listening. I think it's empowering to hear John talk about sight as an expendable, meaningless sense to him now. The fact that he is willing to stop picturing an image of his wife in favor of appreciating her through his other senses is quite incredible.
I would like to believe that I could learn to perceive my world through other senses with such level of detail that sight would start to lose meaning to me. Hell, part of the reason I work in sound design is because our ears can be so much more informative than we give them credit for (and by 'we' I am, of course, referring to the majority of humanity that isn't in sound design...). We often dissect everything our eyes see with such objectivity because sight is our primary survival mechanism, but our ears are also up to the task.
Of course, I'm fortunate. I live in a 1st-world country with above-minimum amenities for both deafness and blindness—and even THEN it's a very hard world to be blind or deaf in. I would have a much different answer if I lived in a place with more danger or fewer health care opportunities.